China has warned the United States that its criticism of the situation in Tibet could harm relations between the two countries.
Chinese Foreign Ministry spokesman Ma Zhaoxu told reporters Wednesday that China is dissatisfied by U.S. comments regarding Tibet.
Ma urged the United States to stop, as he put it, using the Tibet issue to interfere in China's affairs.
On Tuesday, the State Department and White House both voiced concern about the human rights situation in Tibet and called on China to open up a substantive dialogue with the Dalai Lama's representatives.
U.S. officials said that while the United States recognizes Tibet is a part of China, they urged China to reconsider its policies in the remote region that have harmed Tibetan religion, culture and livelihoods.
U.S. lawmakers are also scheduled to vote this week on a nonbinding resolution that calls for a multilateral effort to bring about a peaceful solution to the Tibet issue.
China has urged lawmakers not to pass the resolution.
On Tuesday, Tibetans and their supporters held protests and prayers around the world to mark the 50th anniversary of a failed Tibetan uprising against Chinese rule.
In remarks to thousands of Tibetan exiles in northern India, the Dalai Lama accused China of killing hundreds of thousands of Tibetans and turning the region into "hell on earth." Tibet's exiled spiritual leader said China has brought "untold suffering and destruction" to the Tibetan people, who he says live in constant fear.
China has dismissed the Dalai Lama's accusations and argued that Tibet has enjoyed democratic reforms during 58 years of Chinese rule. China says it liberated Tibetans from the slavery of feudalism.
Residents of Tibet and Tibetan regions of western China have said Chinese security forces increased patrols to prevent people from marking the anniversary with protests.
Chinese authorities have increased security to try to prevent a repeat of last year's mass protests.
China blames the Dalai Lama for instigating the protests as part of efforts to split Tibet from China. But the Buddhist leader denies the charge and says he only wants meaningful autonomy for Tibet inside the borders of China.